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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8091d3057603a19cee5cc97131e780c0d0719b8cb907ff4b4b646134f7025cc' 
  AND token = 'JOjqFHfraxsih4DpzjeSgYrAhHqgXM1mZnV8oBNHO6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}