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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d029c953e42e0ff50c360795f5d7dc043aa21188ab047d7d4fef265c880b7bc' 
  AND token = 'M1aqIWdtMtlfCOTkA4hQ0fVqo+mOEs8rOaTh+pZN/EA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}