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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '71b2a4b0a6b3434dd852002215962d6031c76970cdb5223d4c5592544b103576' 
  AND token = 'lhlboR5Pc/9Vm6+7uLWukLfG2eShuOTU4vPUJMpqCxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}