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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b22ab0a822bd37f6716d6ebd9672bf9dc800a7eea58498d577e7c74838fca799' 
  AND token = 'BSDQCN79FDM/n+p/i4rMWBkGgi5NrLh7uhVaozvh3oY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}