SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '925222e64e63efaf87f8145fced967f3d87947aad8af362f981631986e8b09df' 
  AND token = 'u4gXexIcXmYrdhXvGLyLDcVnZNXUdfKXO5bTvLDZ1+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}