SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae049b7afd45313ef27b1100a4c2adbdb891075f0e838154009a15f668a741cc' 
  AND token = 'RliNS22w1zBzvdyeo4dq9fvf7WnUb4Ua/OSu/h3JtPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}