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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8f5be0b1242c526023b2490d08386d49e618eae82f98129e5ce69ff92d0fc6d' 
  AND token = 'jdxQx+ZLNmpAJ6HwQSb//GqzWScQ1Cnd20/6ZUziFUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}