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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fffb73c21824a6fc2eb7877794c125e807e746a7d63fd77d829d66b48d1e1bb' 
  AND token = 'XzVYucUKB9GLIZAA1CppqA8RxXF58+xE6x1RRG0RF58=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}