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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cd5027d201d6af974da22074be61d7a414e6267a9a999be98e89dd5746d8d0c' 
  AND token = 'g2F5X9HBzXTfUQkMdfs1vvoYDvK7D3KU5xp1hUNq95E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}