SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8fa83b2bd6887750fc48913537ed977f6e1c17507599e1d6d55d70c2c1d3647' 
  AND token = '4T49kzMWRWBXdc94xL1OyHbBKv+OdGtyIcMFk7kFQJM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}