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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39b1f86eb0c322b0240387729b1e1d116cac72f246dbfeb761193bbb37fc84ba' 
  AND token = '+8p3eXZsz4pgFt3Xm45mL7FtIBYf++M/oOoCbNTFZvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}