SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fcf3b3fd1c08e998e3f3d9392d782faf7f073f34113b76ab389a6de1de667eb' 
  AND token = 'M+Oi9eLAux3f62tTV1Q/A1KMEsRB/X2lPCZGbdIF4EI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}