SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '63d45bce0caac0012589d41c552af99367c19c897d779a4af13581b8c7e47f1d' 
  AND token = 'puk/bq2F32ZZKdiDhYINgWoDwE9rvAYXocpKX9EGVMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}