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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed32992a3d18ae90e01b9d455896fa47d31f3266cde34ce6df7ff5c39453b8e' 
  AND token = 'mBkdV+hiZQ/WeQLEma8aBkPeB4kNuRLQPMcOpzOkNXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}