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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e61f40ffa54c9fbc583425e4a515fe341f95abf083fbc8bd9e7666f513e819bd' 
  AND token = 'k6UaH4xYjSt1zvVdeF34TKAJSrs5tNEwKlTdH+H5DRM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}