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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6740b06e04942fe43b74c591144a89b5898ad9905c28b4f21d38e0f8925cc01e' 
  AND token = 'S6yYN+7RRMUPJU3AtttCQYMleZCF2CQ3WK8I9x+NYxE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}