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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e3c4562c98c4ef267fa0c43d9d00342a21aac29177190835e5b02412cd18115' 
  AND token = 'uCNH5KuM6IChjHfnpReoO7u/6dKn6GM8vTUtLLkG4Nc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}