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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6c2c42d20ecdc8026bcbcc4f0e284e49a38bffba216ba6a6cd243e0c70c8510' 
  AND token = 'iG4A7GLqSB1cZItfVOLZdOxnFt9r8MtrqCi2xn2PgME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}