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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48677516fd0fc085370a54158b6c3613f64185fc1bf463e5d7c52e9b562c923d' 
  AND token = 'BpufMFVGMB1MrMaLATuZM0oFi4C3V+yfI3EnagIN8R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}