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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4a7b300d4a104ce09ad3015bdec88eebd2669087b6a84ddb67f1505074e07c1' 
  AND token = 'bit2mZ1dHI45kct6U4iLDJGfgzqeSNca37uprv8PBm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}