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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11c6c56a9bc9e35dec31a7645a6fe0d47ccd81a26470af7a58f342d9fe45117d' 
  AND token = 'Dff7ZF14h6RCbf/fRIYa12kT8pEhRWK5cjwewVNlkIw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}