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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f12a380f9214c69ce3ed53f60ed1c3a51baad39a11acbe230462c91f633d9df' 
  AND token = 'wpTNhYC7y8k9tXc13pBRwNelI9RBgqxHMRNZ4ABkCA0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}