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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e2f09ed5f93af5fac59a75d0bacc303437c2042380e56cd7939cdcb5b0711c2' 
  AND token = '3ADtMHroF+sfn1TRo9tEdhWaxMcWnRGb+XAyqY7HAv0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}