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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '954169aaf0a291c4f679b24d043044d045e98247eb4c628cd1ccf8ffb7d43720' 
  AND token = 'O2nXiudgsHBINugyJbRpU/quT3n+s/318nJ1F955xSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}