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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2523363233d964f1103c4b875d0bdd2388d6bb33edd7ea6811ceced20ca4c31' 
  AND token = 'xVzwjU8DjdscCGurUOYWdqKpLcqpiquYHhVA9d/h2vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}