SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa43e651309b945889312cd4aaf7f85a685b3c29ccb43b16f325e57a6e8f5a8b' 
  AND token = 'g2cv9rDMO4yFG+XD1nLQdAztwcJoaSoHFCxS+5wJ1ms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}