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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60c3975e02de0a57a918eb1801afe856f9d1df5b434e947a195447657d42658b' 
  AND token = 'f1tv46u3DDu0dSMPP46AP3TYK/jsKWFqlNAWOMjf6QE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}