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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4621f0c9a9a30b01d0ff6f21e3381a8219b51f0a98d6d6851fd770f0c1e8f97b' 
  AND token = 'sx5rn1JOIzr6SVsGv37hJQaMgWtFLyE+XpaDt0OOnQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}