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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45ff668839e36e3e38f53aaca3a2d8e4b21e5a90f8c53a00c4acdf34ac540849' 
  AND token = '1o/M1hc+5qTrOjLGK0VtGogVzCrasiJFCFI3tcKZWLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}