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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543523330e4da149700a0a89a64517d4e2f000381a6eb9815fefe300a348d18c' 
  AND token = 'K9rvO/eeItz/kOl+c/kvUtjYjn30p8BO1klny/87ocE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}