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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd8b57970fe2dc290967753b7557c2d410f661487df02d9934c911521b06193c2' 
  AND token = 'YxMXo8Vo/onb2bnQkTGoGz0e+BetUZTfVikYIUsGOIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}