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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3c498e13b57969d373fcf935962b57e32e559aeb5d517ab872cb4cb8aea4440' 
  AND token = 'c+dQnfPfqM8NeCSPfw+wIShmAKO6zk1LzFxj4y5KCn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}