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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f67f5d203ac3f61b2e384ad5e6ff698fb9fcc2433064c4d108cba2406f28337' 
  AND token = 'MB3fx+NmLUMLSQ/ZxqwTcArhHea3n/e6mve7B6qB5co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}