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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf3d7e54f5d43f4598085631411dd6d206453b12608b95594614546498b12417' 
  AND token = 'GMKbPPYfiMFr53/PmJobReCx2AJ8Tqp8Dm2Qm/jfHMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}