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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c225e3c0ff508db4242d8bb45db6fc00ea8be62f687359b64d51a7d2f24a1c59' 
  AND token = '1HNCwH0PWIr9sniBj6+O5W8uz4MP1BZmlXJoIHBFj4U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}