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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ec2c0cd374abc10972f8519fbf8cf4fa8fdf1cb273f9b8c18a3bf8e6847b295' 
  AND token = 'XjGMFQ0g/Lzj+4XZCLVR5wU4G4w+d84M+rsP+1PGwc0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}