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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486bd70e8700179d99230fa834dc759b8596ed19a0adc76b4fb404eb721e26c0' 
  AND token = 'rbquV+2+xhFTFes88NFFYQHWdprOE8RYqHpknjUot5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}