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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2dbc2e3bcfd985183c58224e54845a7936a0e163c5dd315920a0a844e07da0d6' 
  AND token = 'nveTrTD+SkDOsggsj3Q54IvGUNtn/t6q9dTRVrrvVK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}