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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6437a3418da193285af7bf03d289c00cb469519432ca81e4442bffb796742837' 
  AND token = 'gg6dU0VOD9edJ6akR585CuJCS08gsR5DiPMVw2y5Bxc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}