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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dd767ba31a20da3e41a7fbb1b8f2f039e5e110e40554bc8b761918d18c763ac' 
  AND token = 'sB7brCTAOYgimcO/2MvJcd54UbeRk9iYRpB8o0OOqCw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}