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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f2ff96f93e01d92985340ce60f76fe0ebb85fa934594722f4aeb316da17e1e1' 
  AND token = '42APh/203lsECe8QeCcZuZr2U13gNzMK7meb5T0SFCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}