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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7fdb81103fb4427bd73e3ffc8b872b43203cf5d41bb46f8350c8c0ff80165295' 
  AND token = '9ECXJGOUrnuccmGqP9ccoapA1XwbEi4Qrl1hRuIthhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}