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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6666f6e1d653a2f84792c52648873c271d0507ec5d3f1afbde5f3ebc42e073e2' 
  AND token = 'znIglsW9Yc/dk9sy3xnq2EXcHizkcmQMC2+ITpl8rtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}