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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '522eaa640c014d50d94e82ed1fe845973533a9de0103c693d382daf945f08519' 
  AND token = 'f/roq/jd122l/W4N5J5IW8SoayAiZAl08iRYZvzsg/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}