SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c101e83dc3e34e7b3bf972b76e69d9d008eef13f4d339dd578f306ea0fb8420' 
  AND token = 'OhsOGygiWBhKZAQLo3pGkZjMU9kC5gp6AiXfDjSv788=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}