SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12c5289c2a2be18ae0bf3f28f06a6529e208df3a53a72bac28c7cdace04755c3' 
  AND token = 'bjxtNg+0RTsDXyrrS2KlmXzbnEqbobVBkyijlCSWaq4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}