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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e848d68e03974c2e231d12ccd1c86fae338cb8a4656301006e06e0942247fb2' 
  AND token = 'dz7GUbkPOCTcf4PN/V78R8ktVx78rn/E8pIdjL9Div4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}