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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b852472f3f53c8e4bd253e0ba569d42b9165e20161fef54369cfd4043297e0a' 
  AND token = 'CwxawgjtJbVix4K8pyt6rsa5kGBoEFtC12CU0XDvhn4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}