SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fe245fe4bfc456ee4142110384b8c11a7d38f3de15eb9aa05de3ae4f2a47411' 
  AND token = 'I54NZ+8QG0Hd00xtHWYCA5xpX2/H1Cb91E0j8iQmEQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}