SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3a902dfd9e5ef69693ea21ebcd16ba099e039c3c34fde5b8634009e53fce2fbc' 
  AND token = 'AnfYkfpEkcIvoIzBkm9sVZMYq/5ez48MWdKYtBQXcUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}